Interleukins

Interleukin 2 (IL-2) is a protein that occurs naturally in your body. It plays an important role in "switching on" or activating the body's immune system. IL-2 activates special defense cells called "T cells" and "natural killer (NK) cells," to attack and destroy invading germs or diseases.

IL-2 can also stimulate T cells and NK cells to attack and destroy cancer cells. A man-made version of IL-2, called aldesleukin, is available. It acts like natural IL-2 to help the immune system recognize and destroy certain types of melanoma. This treatment is only meant for patients with advanced melanoma (Stage IV) that has spread far from the original site, or to other organs (such as the lungs or liver).

Glossary
Aldesleukin
A manmade version of interleukin-2, a protein released by the immune system that helps fight bacteria, viruses, and some types of cancer cells.
Cancer
A general term for more than 100 different diseases that involve the uncontrolled increase of abnormal new cells. These cells form tumors that can destroy surrounding tissue and spread throughout the body.
IL-2
An agent that stimulates the growth of specific types of white blood cells; used in cancer immunotherapy.
Immune System
The body mechanisms that fight disease by recognizing and neutralizing foreign cells.
Interleukins
Special proteins released by the immune system to fight bacteria, viruses, and other foreign substances.
Melanoma
A highly malignant type of skin cancer that arises in melanocytes, the cells that produce pigment. Melanoma usually begins in a mole.
NK Cells
Specialized cells of the immune system that kill bacteria, viruses, and other foreign substances in the body.
T Cells
Cells of the immune system that recognize "foreign" substances in the body and then help launch an attack.